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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NT5DC1
All Species:
21.52
Human Site:
S278
Identified Species:
47.33
UniProt:
Q5TFE4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TFE4
NP_689942.2
455
51845
S278
E
E
Q
E
A
L
P
S
L
D
K
P
G
W
Y
Chimpanzee
Pan troglodytes
XP_518703
455
51825
S278
E
E
Q
E
A
L
P
S
L
D
K
P
G
W
Y
Rhesus Macaque
Macaca mulatta
XP_001112048
455
51828
S278
E
E
Q
E
A
L
P
S
L
D
K
P
G
W
Y
Dog
Lupus familis
XP_532271
471
53423
A294
E
N
D
E
E
Q
E
A
L
P
S
L
E
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5P5
467
53076
S288
E
E
K
D
E
L
P
S
L
D
K
P
G
W
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507572
133
15081
Chicken
Gallus gallus
XP_419778
454
52040
S277
E
E
Q
E
A
L
L
S
L
D
K
P
G
W
Y
Frog
Xenopus laevis
Q6GN91
499
58768
H306
L
L
W
D
K
I
H
H
L
E
K
G
Q
T
Y
Zebra Danio
Brachydanio rerio
NP_001098413
461
52643
S279
E
D
S
E
G
L
P
S
L
E
K
P
G
W
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121742
508
59601
N332
E
I
I
N
Y
E
E
N
N
I
I
K
S
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197549
242
27677
F66
P
F
H
K
D
R
D
F
C
T
K
G
L
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
83
N.A.
78.5
N.A.
N.A.
24.1
75.1
21.4
62
N.A.
N.A.
25.7
N.A.
24.4
Protein Similarity:
100
100
99.1
87
N.A.
86
N.A.
N.A.
27.2
86.3
39.4
76.7
N.A.
N.A.
42.1
N.A.
34.5
P-Site Identity:
100
100
100
20
N.A.
80
N.A.
N.A.
0
93.3
20
73.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
93.3
N.A.
N.A.
0
93.3
40
86.6
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
37
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
10
10
19
10
0
10
0
0
46
0
0
0
0
10
% D
% Glu:
73
46
0
55
19
10
19
0
0
19
0
0
10
0
0
% E
% Phe:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
10
0
0
0
0
0
0
19
55
0
0
% G
% His:
0
0
10
0
0
0
10
10
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
10
0
0
0
10
10
0
0
0
0
% I
% Lys:
0
0
10
10
10
0
0
0
0
0
73
10
0
19
0
% K
% Leu:
10
10
0
0
0
55
10
0
73
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
46
0
0
10
0
55
0
0
10
% P
% Gln:
0
0
37
0
0
10
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
55
0
0
10
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
55
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
64
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _